The TissueForm Biomaterial Platform has Potential and Proven Scientific Efficacy in Numerous Future Markets

NatruLage: Cartilage Repair

NatruLage is applied by an orthopedic surgeon into a defect in a patients articular cartilage, following drilling into the subchondral bone (microfracture procedure). The material cross-links in the body, and adheres to the surrounding cartilage with no additional adhesives (i.e. without fibrin glue). The tightly packed ECM particles provide mechanical stability needed in the knee joint, while promoting stem and cartilage cell migration into the particles. Over time, the cells begin to produce new cartilage tissue matrix – a regenerative repair response that ensures long term efficacy of the implant.

LINK TO THE SCIENCE: Advanced Functional Materials 2021

Natrulink: 3D Printing Bioink

TissueForm’s biomaterial technology is ideal for producing bioinks for printing realistic tissue-specific scaffolds. Our bioinks (currently in development stage) have the potential to be used as a substrate for cell culture, as an ink to print complex layered tissue-on-a-chip designs, or for tissue engineering solutions. TissueForm has a proof-of-concept grant with our partner laboratory at the University of Colorado Boulder to develop research-grade bioinks with a variety of acellular tissue including cartilage, adipose, kidney, liver, and more.

LINK TO THE SCIENCE: Biofabrication 2022